Five major risk factors for colorectal cancer

So far, the cause of colorectal cancer has not been fully clarified, but it is certain that it is related to the following 5 inducing factors.

1. Excessive consumption of fried and pickled food is one of the risk factors for colorectal cancer.

2. Genetic factors. There are reports of "familial colorectal cancer" both at home and abroad. The number of blood relatives of colorectal cancer patients who died of the disease is significantly higher than that of the general population. Some colorectal adenomas, such as multiple familial adenomatosis, are autosomal dominant genetic diseases with a family prevalence rate of up to 50%. If not treated, there is a possibility of colorectal cancer after the age of 10. Recently, some scholars have studied the relationship between tumor suppressor genes and colorectal cancer and found that the susceptibility and pathogenesis of colorectal cancer are both related to genetic factors.

3. Environmental factors. Studies have shown that among various environmental factors, diet is the most important. The incidence of colorectal cancer is positively correlated with the high fat consumption in food. In addition, it may also be related to the lack of trace elements and changes in lifestyle habits.

4. Colon adenoma. According to the research on autopsy materials from various places, the incidence of colon adenoma is quite consistent with that of colon cancer. According to statistics, the incidence of colon cancer in patients with one adenoma is 5 times higher than that in patients without adenoma, and the incidence of colon cancer in patients with multiple adenomas is 1 times higher than that in patients with a single adenoma.

5. Chronic colon inflammation. The prevalence of colon cancer is positively correlated with the prevalence of schistosomiasis. It is generally believed that due to schistosomiasis, inflammatory changes in the intestines may lead to cancer in some cases. Other chronic inflammations of the intestines may also lead to cancer, such as ulcerative colitis, which has a 3% to 5% chance of cancer.