The main histological changes of chronic laryngitis are also epithelial hyperplasia and degeneration, which are basically the same as those of laryngeal thick skin disease, and only differ in degree, that is, the latter can be identified with the naked eye. Therefore, chronic laryngitis is indirectly related to laryngeal cancer. Chronic laryngitis requires biopsy in the following cases: long course of disease, gradual aggravation, patients over 45 years old, symptoms only temporarily relieved or no significant improvement after regular treatment, and laryngeal mucosal lesions (such as edema-like protrusions on the vocal cords or localized white spots, etc.) never completely disappear. If the biopsy report shows only simple localized flat epithelial hyperplasia, the lesion can be carefully removed under a supporting laryngoscope or laryngeal endoscope, and the follow-up should be at least 1 year after surgery. If epithelial hyperplasia or white spots are extended, the lesion should be carefully removed under a surgical microscope. Before removal, smear the mucosal surface with 3% acetic acid to remove mucus and facilitate identification of lesions. |
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