What is the mid-term cure rate for laryngeal cancer

As air pollution becomes more and more serious, various smog weathers appear more frequently, which brings many diseases to people's respiratory system. The occurrence of laryngeal cancer has become a large group in society. So how should we deal with this situation? How should we treat it? What is its cure rate?

Generally speaking, the cure rate of early laryngeal cancer can be as high as 90%. For radical laryngeal cancer, if there is a local recurrence, total laryngectomy can still have a cure rate of 68%. For patients who relapse after radical surgery, the curative effect of radiotherapy is very poor, and the cure rate does not exceed 10%. The cure rates of surgery and radiotherapy for stage I laryngeal cancer are both over 90%. Stage II and some stage III tumors can undergo surgery to preserve laryngeal function, sometimes including neck dissection. For stage I or stage II voice reconstruction surgery, some patients can acquire language communication ability. After surgery, voice function can also be acquired through esophageal voice, artificial voice generator, etc. Advanced laryngeal cancer should be treated with total laryngectomy, which sometimes must include neck dissection.

Currently, the treatment of laryngeal cancer includes surgery, radiotherapy, chemotherapy and biological therapy, etc. Sometimes multiple treatment methods are combined to improve the 5-year survival rate of laryngeal cancer, maximize the retention of the patient's laryngeal vocal function, and improve the patient's quality of life.

Surgery

In histology and embryology, the left and right sides of the larynx develop independently, and the supraglottis, glottis and subglottis come from different primordia; the left and right lymphatic drainage is not connected to each other, and the supraglottis, glottis and subglottis lymphatic drainage are independent, which provides a basis for surgical treatment of the larynx, especially partial resection. Different surgical procedures can be used according to the different locations of the cancer.

(1) Laryngeal carcinoma in situ or mild invasive lesions are suitable for laryngeal laser surgery and plasma surgery. They have the advantages of minimally invasive, less bleeding, low tumor spread rate, and good preservation of voice function. They are mainly suitable for early stage cases.

(2) Partial laryngectomy includes laryngeal dehiscence and vocal cord resection; frontal partial laryngectomy; vertical hemilaryngectomy; and some corresponding modified procedures are selected according to the extent of glottic cancer invasion.

(3) Supraglottic laryngectomy is suitable for supraglottic cancer.

(4) Total laryngectomy is suitable for advanced laryngeal cancer.

Although there are many treatments for laryngeal cancer, its cure rate is still not very high, which means that many patients will lose their precious lives because of it. Therefore, in order to greatly improve the cure rate of the disease, patients and doctors need to work together to deal with it so that they can live a better life.