What is the cause of baby bone cancer? Bone tumor is an orthopedic disease. Many people are tortured by the disease because of bone tumor. Severe cases will affect their life and work, bringing many inconveniences to their lives. There are many reasons for the disease in life. Let us learn about the causes of the disease: What are the main causes of bone tumors? The mechanism of cancer pain caused by bone metastasis comes from the chemical and mechanical stimulation exerted by tumor cells on the nociceptors on the bone or periosteum, as well as the pain caused by the tumor infiltration of sensory nerves by bone tumors. It is generally believed that the causes of acute bone tumors include bone destruction, pathological fractures, periosteum involvement, nerve infiltration, and activation of nociceptors by neurotransmitters released by tumors. When bone tumors destroy bone, they produce prostaglandin E1 (PGE1) and prostaglandin E2 (PGE2), which can sensitize peripheral nerve endings; this persistent pain can cause sensitization of nociceptors (overreaction to harmful or non-harmful stimuli), and clinically, bone tumor patients show abnormal pain and hyperalgesia. Therefore, this is also a factor leading to the etiology of bone tumors. Through understanding, I believe everyone has a new understanding and knowledge of the causes of bone tumors. There are always many diseases happening around us in life, and bone tumors are a very serious one, so we must not take it lightly. When we have symptoms of the disease, we must seek timely treatment. |
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