Common methods for treating teratoma

Even a relatively minor disease can cause harm to our body, not to mention a more serious tumor. Experts say that although teratoma is a benign disease, it can also become malignant. Therefore, for this disease, we should treat it as soon as possible. So, what are the common methods of treating teratoma? Let's introduce them in detail below.

1. Surgical treatment

Once a teratoma is diagnosed, surgery should be performed as soon as possible. For cases diagnosed with malignant tumors (a tumor is an abnormal lesion formed by the loss of normal regulation of the growth of a cell in a local tissue at the genetic level under the influence of various carcinogenic factors, resulting in its clonal abnormal proliferation.), chemotherapy should be performed before surgery to create conditions for elective surgery.

2. Chemotherapy

For mixed teratomas, only chlorambucil (CI, B) can be used, at 0.1 mg/(kgd) orally for 12 weeks. For malignant teratomas, chemotherapy should be given after surgical resection. Commonly used chemotherapy regimens are as follows: ① POMB/ACE alternating therapy: POMB regimen: vincristine (VCR) 1.5 mg/m2, intravenous injection, day 1; methotrexate (MTX) 100 mg/m2. Intravenous drip (lasting 12 hours), day 1; calcium folinate (CF) rescue, 15 mg, once/12 hours, days 2 and 3; bleomycin (BLM) 10-20 mg/m2, intravenous injection (lasting 24 hours), day 3; cisplatin (DDP) 60 mg/m2, intravenous drip, day 4; 2 weeks as a course of treatment. ACE regimen: etoposide (VP16) 100mg/m2, intravenous injection, days 1 to 5; actinomycin D (ACD) 0.45mg/m2, intravenous injection, days 3 to 5; cyclophosphamide (CTX) 500mg/m2, intravenous injection, day 5; 2 weeks as a course of treatment. After POMB2 courses, PONfB and ACE are used alternately. The total course of treatment is 1 year. DVB regimen: DDP 20mg/m2, intravenous injection, days 1 to 5; vinblastine (VLB) 0.15-0.2mg/kg, intravenous injection, days 1 and 2; BLM 10-20mg/m2, intravenous injection, days 1, 8, and 15. Every 3 weeks is a course of treatment. After 4 courses of treatment, surgery was performed, and CA chemotherapy was given after surgery: CA chemotherapy: CTX 500 mg/m2, intravenous injection, day 1; doxorubicin (ADR) 50 mg/m2, intravenous injection, day 1. For patients with residual tumor, 10 times/3 weeks; for patients without residual tumor, 5 times/3 weeks.

3. Immunotherapy

Transfer factor, 1-2 times a week, 1 vial each time. Or use short anaerobic bacteriocin at the same time, starting from 0.1ml/time, once a week, increasing by 0.1ml each time, until 2ml/time, for 2 years.

4. Radiation therapy

Currently, the instrument is used in cases of malignant teratomas with microscopic or macroscopic residuals.

In the treatment of teratoma, in addition to active medication, we should also take comprehensive nursing measures. The above content is about the treatment measures for teratoma. Have you mastered it clearly? Experts suggest that when we choose a treatment method, we should consider it comprehensively instead of choosing it randomly.