How do osteosarcoma patients self-diagnose

Everyone knows that osteosarcoma needs to be diagnosed through some examinations. Osteosarcoma is still a disease with a high mortality rate among children and adolescents, but early detection and timely treatment have greatly improved the survival rate of the disease. Can osteosarcoma be self-diagnosed? Let's learn how osteosarcoma patients can self-diagnose.

Osteosarcoma is common in adolescents aged 15 to 25 years old, and is prone to occur in the metaphysis of the long bones of the limbs. It is most common above and below the knee joint. Osteosarcoma is common in adolescents aged 15 to 25 years old, and is prone to occur in the metaphysis of the long bones of the limbs. It is most common above and below the knee joint. Osteosarcoma (OS) is a primary malignant bone tumor derived from mesenchymal tissue, and its incidence ranks second among primary bone tumors. The most common age is 10 to 25 years old, and males are slightly more than females. Its most common sites are the metaphysis of long bones, with the distal femur and proximal tibia being the most common. Osteosarcoma is highly malignant, prone to early lung metastasis, and has a poor prognosis.

Clinical manifestations 1. Pain: caused by the traction of the periosteum. Characteristics: mild to severe; intermittent to continuous; pain at night; pain at rest.

2. Lumps: There may be local lumps with varying hardness. The affected area may have increased skin temperature and venous distension.

3. Functional impairment: limited joint movement.

4. Pathological fracture.

5. Symptoms of cachexia such as anemia, weight loss, and loss of appetite.

Laboratory tests

It is reported that laboratory tests such as alkaline phosphatase are closely related to the diagnosis and prognosis of osteosarcoma. Some patients may have elevated alkaline phosphatase, increased erythrocyte sedimentation rate, and increased white blood cell count. Patients should be examined before receiving neoadjuvant chemotherapy, and blood routine, liver and kidney function, and alkaline phosphatase should be regularly monitored during chemotherapy. In recent years, many studies have shown that the levels of miRNAs in peripheral blood or tissues can effectively predict the stage, severity, and prognosis of osteosarcoma, such as miR-21, miR-199a-3p, and miR-29.

Imaging tests

In summary, patients with the above clinical manifestations, abnormal results of corresponding laboratory test indicators, and abnormal imaging changes should be referred to a professional bone tumor diagnosis and treatment center for treatment.