Hepatitis A symptoms self-test_How to check hepatitis A

I believe many people do not know what the symptoms of hepatitis A are, and hepatitis A can only be detected by going to the hospital for a hepatitis B two-pair-and-a-half test. The method for checking hepatitis A is to check the metabolic function of protein and the content of serum enzymes, generally by testing the transaminase content in the blood. If the transaminase content is too high, then liver diseases such as hepatitis A and hepatitis B may exist.

How to check for hepatitis A

1. Protein metabolism function experiment

Thymol turbidity test and serum hyaluronic acid test both showed increases. Decreased serum albumin and increased globulin are indicators of chronic active hepatitis and cirrhosis. Acute hepatitis is often normal.

2. Specific serological examination

Detection of anti-HAVIgM is an important indicator for diagnosing hepatitis A and is the most reliable and sensitive method for diagnosing hepatitis A. If the anti-HAV IgM test is positive, current infection can be confirmed; if it is negative, it can be ruled out.

3. Serum enzyme assay

Serum alanine aminotransferase (ALT) begins to increase in the early stage of pre-icterus, and serum bilirubin increases at the end of the pre-icterus. The peak level of serum ALT occurs before the peak level of serum bilirubin and generally returns to normal one to several weeks after jaundice subsides. Determination of ALT is helpful for the diagnosis of early hepatitis. ALT elevation is not specific. A single ALT increase of more than 2 times the normal value is of diagnostic value only when other causes are excluded and combined with clinical manifestations and immunological dynamic observations. The acute anicteric type and subclinical type are often characterized by a single increase in ALT. Generally, the level of ALT in serum is related to the degree of liver cell necrosis. In severe hepatitis, jaundice rapidly deepens, while ALP decreases, showing bile enzyme separation, indicating massive liver cell necrosis. Serum alkaline phosphatase (ALP) is elevated in cholestatic hepatitis, but not as significantly as in extrahepatic obstructive jaundice. When liver damage is severe, serum cholinesterase activity is significantly reduced. Lactate dehydrogenase isoenzymes are also of reference value.

4. Pigment metabolism function determination

Commonly used tests include total bilirubin and direct bilirubin determination, and urine tribilirubin examination. In patients with jaundice, both serum total bilirubin and direct bilirubin are elevated. The increase is more significant in patients with cholestatic type, accompanied by a significant increase in ALP and gamma-glutamyl transpeptidase (γ-GT). For the anicteric type, the incisional cyanine green (ICG) retention test or the sodium sulfabromophthalein retention test can be used to assist in the diagnosis.