Many people do not understand scar hyperplasia. In fact, it is mainly manifested in the inflammatory reaction during the wound healing process. This is also caused by infection caused by lack of care for the wound surface and changes in local skin tension, resulting in scar hyperplasia. 1. Wound During the wound healing process, an inflammatory response occurs first, and then myofibroblasts appear in the wound, divide and proliferate to synthesize collagen fibers, causing collagen deposition to form scars. 2. Infection If the wound is infected, on the one hand, the remaining epithelial cells are destroyed, causing the wound to deepen and the healing time to be prolonged; on the other hand, inflammatory factors stimulate the proliferation of fibroblasts, and repeated infections will cause abnormal proliferation of granulation tissue. Infiltration of inflammatory cells is a characteristic of granulation tissue. Infection increases the number of inflammatory cells. The more fibroblasts there are, the more likely scar hyperplasia will occur. 3. Changes in local skin tension The direction of the scar is inconsistent with the skin tension, resulting in chronic traction, which is a factor in scar hyperplasia. 4. Age Adolescents are in the puberty stage, with vigorous tissue growth, strong immune response after trauma, high skin tension, and prone to scar hyperplasia. 5. Pigment People of color have more skin pigment cells, which are more likely to cause scars. The incidence of scars in blacks is about twice that of whites, and the incidence of burn scars in my country is also quite high. 6. Surgery If people with scar-prone constitution adopt surgical excision treatment, it will stimulate fibroblasts, causing repeated scar proliferation. Therefore, surgical excision treatment should be strictly prohibited for people with scar-prone constitution. 7. Others Foreign body stimulation can also cause scar hyperplasia. Common foreign bodies include dust, talcum powder, cotton fibers, thread knots, etc. |
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