What are the methods for identifying latent glomerulonephritis?

Latent glomerulonephritis is a disease with a relatively high incidence in daily life. Most patients have no obvious symptoms and signs. Only some patients will experience symptoms such as low back pain and fatigue. Therefore, it is easy to be ignored. Therefore, people must understand the following identification methods in order to detect and treat this disease early.

1. Excluding hematuria and proteinuria caused by urinary tract inflammation, the inflammatory response of the urinary tract after general infection or tuberculosis infection can lead to hematuria and proteinuria. However, they are generally accompanied by leukocyturia and typical urethral irritation, and multiple bacterial cultures of urine may give positive results. The morphology of red blood cells in the original is mostly single type, that is, non-nephrogenic.

2. Excluding secondary and hereditary glomerular diseases, secondary glomerular diseases generally have other manifestations of the underlying diseases in addition to asymptomatic hematuria and proteinuria. For example, patients with Henoch-Schonlein purpura nephritis may have symptoms such as rash, joint pain, abdominal pain, etc., and sometimes the cause of the allergy can be found. The renal pathological changes in systemic lupus nephritis are varied and can be very mild. Typical manifestations of glomerular disease may not appear clinically. It is mainly diagnosed through pathological differential diagnosis, and most patients are young women. Mild hepatitis B-related nephritis and hereditary progressive nephritis may manifest as hematuria and proteinuria in the early stages and should be carefully excluded. For patients with simple microalbuminuria, diabetic nephropathy and early amyloidosis damage should be ruled out.

3. The diagnosis of asymptomatic hematuria is mainly based on the method of exclusion. For adolescent patients with abnormal urinary red blood cell morphology and reduced volume, glomerular disease should be suspected first, but various secondary glomerular diseases should be excluded, such as Henoch-Schonlein purpura, systemic lupus erythematosus and hereditary progressive nephritis. Idiopathic hypercalciuria should be excluded in young children. Young athletes should pay attention to the relationship between hematuria and strenuous exercise to rule out "jogger's nephritis." Women of childbearing age who have a history of taking estrogen-containing contraceptives should be excluded from low back pain-hematuria syndrome. Elderly patients should be careful to exclude surgical hematuria and should undergo intravenous pyelography, retrograde pyelography, cystoscopy, prostate examination, and, if necessary, renal artery angiography, kidney CT, MRI and other examinations.

How to differentially diagnose latent glomerulonephritis? In fact, it can be identified through some of the diseases mentioned above. For this latent glomerulonephritis, active differential diagnosis is the most reliable. At present, only active identification can tell whether it is such a disease.