The main uses and synthesis methods of isomyristate

Isomyristate is a substance widely used in cosmetics. Its main function is moisturizing and has the effect of nourishing the skin. Commonly used items such as lipsticks, powders, and lip balms contain isomyristate. In addition, myristic acid isopropyl ester can also be used to make lubricants for emulsion cosmetics. Below we will introduce in detail the main uses and synthesis methods of myristic acid isoester!

Isopropyl myristate

It is widely used in cosmetics to moisturize and hydrate the skin. The skin has a good absorption of this product, and it can effectively contact the hair follicles in the cortex, penetrate deep into the cortex, and bring in the active components in the cosmetics to give full play to the role of the effective ingredients. As a cosmetic solvent, skin moisturizer and penetrant.

Main Application

1. Used as a dispersant for lipstick, hair cream, lip balm, cleaning cream, perfume powder and medical ointment. It can also be used as a perfume fixative and as a dispersant and raw material in the pharmaceutical industry. This product is one of the important additives for mid- to high-end cosmetics. It has excellent penetrating, moisturizing and softening effects on the skin and is used as an emulsifier and wetting agent for cosmetics.

2. Synthetic grease. Mainly used as a lubricant in emulsion cosmetics. It has good compatibility with other cosmetic raw materials and can improve the affinity of cosmetics to the skin. Since it is slightly irritating to the skin, do not use too much.

Synthesis method

1. It is obtained by esterifying myristic acid obtained by redistillation of coconut oil with isopropyl alcohol.

2. Add 200 kg of tetradecanoic acid and 450 kg of isopropanol into the reactor in sequence, mix and add 360 kg (98%) sulfuric acid, heat and reflux for 10 hours, recover isopropanol, wash the acid with ice water, neutralize with 10% Na2CO3 aqueous solution, evaporate isopropanol and water under normal pressure, and evaporate the product under reduced pressure at 185 ℃/2.0 kPa～195 ℃/2.7 kPa.

3. Add 90 kg of isopropanol into the reactor, and then add sulfuric acid equivalent to 5% of the total amount of feed as a catalyst. Slowly add 228 kg of tetradecanoic acid under stirring, heat to reflux, and continuously separate water. After reacting until no water is separated, cool down and take samples to measure the acid value. The end point is when the acid value reaches 1.5 mg KOH/g. Add alkali for neutralization, remove water under reduced pressure, and then dealcoholize under reduced pressure to an acid value of 0.05-1.0 mg KOH/g. The output is the finished product.

4. Acidification method is mainly used. It is prepared by separating myristic acid from coconut oleic acid and then adding isopropanol for esterification.