Everyone has a certain amount of muscles in their body, and the strength of each person's muscles is different. For people with strong bodies, their muscles tend to be stronger, but there is a substance in the muscles called creatinine, which is a metabolite produced by the muscles. Many people check their creatinine levels when they go to the hospital for a checkup. So is it normal to see a value of 75 after checking the creatinine level? Normal, this is the normal level of creatinine in humans, Creatinine (Cre) is a product of muscle metabolism in the human body and is mainly excreted from the body through glomerular filtration. Every 20g of muscle metabolism can produce 1mg of creatinine. When the intake of meat food is stable and there is no major change in the body's muscle metabolism, the production of creatinine will be relatively constant. Creatinine in the blood comes from both exogenous and endogenous sources. Exogenous creatinine is the product of meat metabolism in the body; endogenous creatinine is the product of muscle tissue metabolism in the body. Reference range Serum creatinine: normal serum creatinine Male 54-106 μmoI/L Female 44-97 μmol/L Children: 24.9-69.7 μmol/L Urine creatinine: creatinine mainly comes from the blood and is excreted in the urine after being filtered through the glomerulus. [Reference value] 8.4-13.25mmol/24 hours urine or 40mg/dl to 130mg/dl is normal. Urine creatinine 90% of the body's creatine is found in muscles, and most of it is in the form of creatine phosphate. Creatine phosphate is dephosphorylated to form creatinine, which is excreted in the urine as urinary creatinine. The daily excretion of creatinine in normal human urine is quite stable, ranging from 1.0 to 1.8 g for adult males and 0.7 to 1.0 g for females. It is also not affected by food protein content or urine volume. The number of milligrams of urine creatinine excreted per kilogram of body weight in 24 hours is called the urine creatinine coefficient. The normal creatinine coefficient is: 18~32 for men and 10~25 for women. The urine creatinine coefficient of athletes is higher than that of ordinary people, generally ranging from 25 to 40. The urine creatinine coefficients of athletes in different events are also different. Athletes who train in strength and speed events have well-developed muscles and high urine creatinine coefficients. The daily excretion of urine creatinine is highly correlated with athletic performance. 8.4-13.25mmol/24 hours urine or 40mg/dl to 130mg/dl is normal. Increase: seen in acromegaly, gigantism, diabetes, infection, hypothyroidism, meat consumption, exercise, and medication intake (such as vitamin C, levodopa, methyldopa, etc.). Decreased: seen in acute or chronic renal insufficiency, severe congestive heart failure, hyperthyroidism, anemia, muscular dystrophy, leukemia, vegetarians, and those taking androgens, thiazide drugs, etc. |
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