How to reduce the recurrence of ovarian cancer!

How to reduce the recurrence of ovarian cancer!

During ovarian cancer surgery, the primary tumor and visible pelvic and abdominal metastases should be removed as much as possible, or the diameter of the residual tumor should be reduced to less than 2.0 to 1.5 cm. For epithelial cancer, the greater omentum and appendix should also be removed.

The treatment of intestinal metastasis is an important part of ovarian cancer surgery and one of the determinants of prognosis. For shallowly infiltrating cancerous masses, removal surgery is feasible; however, for larger masses or deeper infiltration, intestinal resection and anastomosis should be resolutely performed. The transverse colon, sigmoid colon, and rectum are the most affected by intestinal metastasis or involvement. If there is still 8 to 10 cm of rectum left after the sigmoid colon and rectum are removed, anastomosis should be performed as much as possible; if it is difficult to anastomose or the tissue at the end is unhealthy, colostomy is required. An intestinal stapler can be used to complete end-to-end or end-to-side anastomosis during low rectal resection, which is fast, effective, and can avoid the pain of colostomy. Small implanted nodules in the liver, spleen, and diaphragm generally do not need to be removed, but rely on chemotherapy to eliminate them; large cancerous masses should be removed as much as possible. The lymph node metastasis rate of ovarian cancer is as high as more than 50%. At present, most experiences have tended to lymph node removal as a component of tumor cell reduction surgery. It is more beneficial to remove the retroperitoneal lymph nodes in patients who can remove the primary and secondary lesions. If the primary tumor or metastatic tumor cannot achieve cytoreduction, forced lymph node removal will be of no benefit.

Long-term chemotherapy is necessary to reduce the recurrence of ovarian cancer

Chemotherapy for ovarian cancer should be long-term and continuous, especially for those in the advanced stage and those who cannot be removed by surgery. The medication plan is: one course of treatment per month in the first year after surgery; one course of treatment per month in the second year; one course of treatment every 6 months in the third year; one course of treatment every 6 months in the fourth to fifth year, and oral medication is often used.

The treatment varies according to clinical stage, tissue differentiation, thoroughness of surgical resection, patient response, etc. After 5 years, if there is no sign of recurrence, the drug can be discontinued. Try to avoid stopping chemotherapy midway, as stopping chemotherapy midway can increase the possibility of recurrence of ovarian malignant tumors. If you have other questions about ovarian cancer, please click on the online experts to help you answer! ~


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