What are the main causes of skin cancer?

What are the main causes of skin cancer? I believe many people have this question. Only when we understand the cause can we carry out more targeted treatment. Let us follow the experts to understand the causes of skin cancer .

1. Daily exposure to the sun and ultraviolet radiation: There is sufficient evidence to support that ultraviolet radiation, the protection of human melanin and the interaction of the immune system function lead to the occurrence of skin cancer. This is one of the main causes of skin cancer. When measuring human skin in sunlight, the parts of the skin that receive the most ultraviolet rays are the head, face, back of the neck, and hands, and squamous cell carcinoma almost all occur in these parts. The carcinogenic mechanism of ultraviolet rays may be that the photochemical effect changes the structure of cell DNA, while destroying the active antigen structure on the surface of lymphocytes, reducing the body's immune function, and leading to the occurrence of skin cancer with the participation of other cancer-promoting factors.

2. Chemical carcinogens: About 100 years after Percivall first described the report of chimney sweeps being prone to scrotal skin cancer, people discovered that workers who frequently come into contact with arsenic, tar and asphalt are prone to skin cancer. Chemical carcinogenesis can be divided into two periods, the initiation period and the promotion period. The initiation period to the induced results are closely related to the exposure limit of the specific substance or carcinogen, and its progress is irreversible, and cell changes are related to genetics. The promotion period requires repeated exposure to the contact material, which is related to the interval time. If there is no exposure for a long time, it can still be reversed and no cancer will occur. The interval between the initiation period and the promotion period is very important, and there can be two results, namely the formation or non-formation of skin cancer.

3. Ionizing radiation: In the past, skin cancer was caused by radiation workers who neglected protective measures, which led to radiation-induced dry skin. In recent years, due to the improvement of radiation equipment and radiation technology, especially the strengthening of various protective measures, occupational skin cancer has basically disappeared. However, some patients who have received radiotherapy may still develop skin cancer in the radiation field after several years. This is also a cause of skin cancer.

4. Chronic irritation and inflammation: Malignant skin tumors can occur and develop in scars, chronic ulcers, fistulas, and sinus tracts. Some Asian people are addicted to chewing tobacco or betel nuts, so squamous cell carcinoma is prone to occur in the mouth or lips.

The above is an introduction to the causes of skin cancer. I hope the above content can be helpful to you. If you have any questions about skin cancer, you can contact our online experts and they will give you detailed answers.

For more information, please visit the skin cancer special page at http://www..com.cn/zhongliu/pfa/ or consult an expert for free. The expert will then give a detailed answer based on the patient's specific situation.