Sequelae of chemotherapy for nasopharyngeal carcinoma

Chemotherapy is an effective method for treating nasopharyngeal carcinoma, but patients with nasopharyngeal carcinoma often experience some sequelae after chemotherapy, which is very detrimental to the patient's health. What are the common sequelae of nasopharyngeal carcinoma after chemotherapy? The following will tell you about the common sequelae of nasopharyngeal carcinoma after chemotherapy.

In general, the common sequelae of nasopharyngeal carcinoma after chemotherapy are:

1. Local reaction: This sequela of nasopharyngeal carcinoma includes reactions of the skin, mucous membranes, and salivary glands. Skin reactions manifest as dry dermatitis or even wet dermatitis. Anti-inflammatory ointments with 0.1% borneol talc or lanolin as the base can be used topically. Mucosal reactions manifest as congestion, edema, exudation, and accumulation of secretions in the nasopharyngeal and oropharyngeal mucosa. Gargles and lubricating anti-inflammatory agents can be used topically. In a few patients, parotid swelling may occur after 2Gy of parotid irradiation, and the swelling gradually subsides in 2 to 3 days. When irradiated with 40Gy, saliva secretion is significantly reduced, while oral mucosal secretion increases, and the mucosa becomes congested and swollen. Patients have dry mouth and difficulty eating dry food. Therefore, excessive irradiation of the parotid gland should be avoided. These are all common sequelae of nasopharyngeal carcinoma after chemotherapy.

2. Systemic reaction: The sequelae of nasopharyngeal carcinoma also include fatigue, dizziness, decreased appetite, nausea, vomiting, tastelessness or change in taste in the mouth, insomnia or drowsiness, etc. Some patients may have sequelae of nasopharyngeal carcinoma with changes in blood count, especially leukopenia. Although the degree varies, it can generally be overcome through symptomatic treatment and radiotherapy can be completed. If necessary, vitamin B1, B6, C, metoclopramide, etc. can be taken. If the white blood cell count drops below 3×109, radiotherapy should be suspended.

The above is an introduction to the common sequelae of nasopharyngeal carcinoma after chemotherapy. I believe everyone has some understanding of this. For more questions about the sequelae of nasopharyngeal carcinoma, you can consult our online experts, who will give you detailed answers.