Pathological diagnosis is achieved by completely removing the tumor or removing a portion of the tumor tissue. After many steps of processing, the pathologist observes the morphology and other intrinsic characteristics of the tissue cells under a microscope, analyzes and determines the final diagnosis of the tumor. It is the "gold standard" for the diagnosis of all malignant tumors. Regardless of the depth, location, size, shape, or hardness of the lesion, a biopsy is necessary to diagnose or rule out lymphoma. Superficial lymph nodes can be directly excised and biopsied, while deep lesions require core needle puncture biopsy under B-ultrasound or CT guidance. Lesions in the gastrointestinal tract, nasopharynx, and respiratory tract can be examined endoscopically and biopsied, while lesions in the chest, pelvis, and abdomen can be examined and biopsied by thoracotomy or laparoscopy. If necessary, laparotomy or thoracotomy may be required to obtain pathological tissue. So, can lymphoma metastasize through the membrane damaged by puncture? Theoretically, this situation exists, but patients may wish to weigh the pros and cons. If it is really a malignant tumor, even without puncture, as the disease progresses, tumor cells will break through the membrane and invade adjacent or even distant organs and tissues. Another characteristic of malignant tumors is that they can spread widely with blood and lymph, which is not controlled by the capsule at all. However, no examination method can replace pathological diagnosis. How can we get a correct pathological diagnosis without puncture or biopsy? Any blind treatment is extremely dangerous and will cause great harm to the patient. |
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