Five high-risk factors for rectal cancer

There are many high-risk factors that lead to rectal cancer, and it is important for us to understand these and take preventive measures.

1. Genetic factors Except for patients with colorectal cancer caused by familial polyposis or malignant transformation of ulcerative colitis, about 5% to 10% of other colorectal cancer patients have a clear family history of tumors, which is one of the causes of colorectal cancer.

2. People with low serum cholesterol have a higher incidence of colorectal cancer. People with serum cholesterol below 110 mg/dl have a risk of colorectal cancer more than three times higher than normal people. So this is also an important factor leading to colorectal cancer.

3. High fat and low fiber are both carcinogens or co-carcinogens. Patients with a high proportion of animal fat and protein and low fiber content in their diet have a significantly higher incidence rate. This is because this situation will slow down intestinal peristalsis, increase the absorption of intestinal toxins, and accelerate the occurrence of rectal cancer.

4. Holding back urine and feces Holding back urine and feces is one of the causes of colorectal cancer, because urine contains a variety of carcinogens, all of which can stimulate the bladder epithelium to become cancerous; feces contains more harmful substances, such as hydrogen sulfide, skatole, cholesterol metabolites and secondary bile acids, which can also cause colorectal cancer if they frequently stimulate the intestinal mucosa.

5. Chronic colitis, especially chronic ulcerative colitis, and granulomas caused by chronic schistosomiasis are directly related to the occurrence of rectal cancer. The longer the course of the disease, the higher the possibility of colorectal cancer. The incidence of rectal cancer in patients with ulcerative colitis for more than 20 years is about 20% to 40%.