Is primary gallbladder cancer hereditary?

Nowadays, gallbladder cancer is not rare, and the incidence is increasing year by year. Women over 60 years old are more likely to suffer from this disease, and the incidence rate is higher in northwest China. So, can gallbladder cancer really be passed on to the next generation? This is a question that many patients are concerned about. For this reason, we specially answer your questions and hope to help patients.

First of all, is gallbladder cancer hereditary? First, we need to know what are the causes of gallbladder cancer?

It is transformed from normal cells. The division of cancer cells is difficult to control. When the number of cancer cells in human cells exceeds 1 million, some symptoms of cancer will occur. So how do normal cells mutate into cancer cells? For example, viruses, radiation, and chemicals act on the DNA in cells, causing changes in its structure or function, which leads to changes in metabolism. Changes in cell proliferation become cancer cells. DNA is the basic substance of heredity. Once DNA changes, it will be passed on to the next generation. In this sense, gallbladder cancer is related to heredity.

Secondly, the cells of the parents become cancerous. When the DNA in the reproductive cells of the father and mother becomes cancerous, all the cells in their children's bodies acquire this changed genetic information and may become cancerous. This is a "hereditary" cancer. However, the DNA of somatic cells changes in the acquired environment and becomes cancerous cells. Then the daughter cells generated by the division of this cell are still cancerous cells. It will not affect the cancerous DNA in the reproductive cells, so this cancer cell will not be inherited by the children. This is a "non-hereditary" cancer.

In recent years, with the advent of biological therapy, there have been new breakthroughs in the treatment of malignant tumors. Multicellular immunotherapy refers to a treatment method that uses various biological agents and biotechnological means to regulate and enhance the body's immunity and anti-cancer ability to inhibit and kill cancer cells. The effect of biological treatment after tumor surgery can effectively inhibit residual cancer and promote the recovery of patients' body functions. Even for patients who have undergone relatively complete surgical resection in the early stage, certain postoperative treatment measures should be taken to inhibit the recurrence and metastasis of invisible cancer cells and accelerate the recovery of patients' physical fitness.