How to treat liver cancer cells that spread to the blood

Cancer cells encounter many difficulties during the metastasis process. First, they must undergo dozens of mutations, then overcome intercellular adhesion to break away, and change their shape to pass through dense connective tissue. After successfully escaping, cancer cells will enter the blood through microvessels, where they may also be attacked by white blood cells. Next, cancer cells will enter a new organ through microvessels (now called "micrometastasis"). So how to treat liver cancer cells that spread to the blood?

Here, cancer cells face an unfriendly environment (called a "microenvironment"). Some cells die immediately, some divide several times and then die, and some remain dormant, with a survival rate of only one in hundreds of millions. The surviving cancer cells can regenerate and colonize, becoming "visible metastasis" that can be found in laboratory tests. As metastasis develops, it squeezes out normal cells, destroys the function of organs, and is ultimately fatal. Suggestions: Cancer cells enter the blood and spread throughout the body with the blood, and can only be treated with chemotherapy. However, it is generally not possible to kill them all.